Bryn Monnery

Office: C108A

+3211268160bryn.monnery@uhasselt.be

Scientific Contributions

[19] Synthesis of defined high molar mass poly (2-methyl-2-oxazoline)

O. Sedlacek, B.D. Monnery, R. Hoogenboom, Polym. Chem. 2019, 10, 1286-1290. DOI: 10.1039/C9PY00013E

[18] High molar mass poly(2-oxazoline)s

B.D. Monnery, O. Sedleck, V.V. Jerca, B. Verbraeken, R. Cavill and R. Hoogenboom, Angew. Chem. Int. Ed. 2018, 57, 15400-15404. DOI: 10.1002/anie.201807796

[17] A. Gubarev, B.D. Monnery, A.A. Lezov, O. Sedlacek, N.V. Tsvetkov, R. Hoogenboom, S.K. Filippov; Conformational properties of biocompatible poly (2-ethyl-2-oxazoline)s in phosphate buffered saline

A. Gubarev, B.D. Monnery, A.A. Lezov, O. Sedlacek, N.V. Tsvetkov, R. Hoogenboom, S.K. Filippov, Polym. Chem. 2018, 9, 2232-7. DOI: 10.1039/C8PY00255J

[16] Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues

O. Sedlacek, B.D. Monnery, J. Mattova, J. Kucka, J. Panek, O. Janouskova, A. Hocherl, M. Zadinova, R. Hoogenboom and M. Hruby, Biomaterials 2017, 146, 1-12. DOI: 10.1016/j.biomaterials.2017.09.003

[15] Cytotoxicity of polycations: relationship of molecular weight and the hydrolytic theory of the mechanism of toxicity

B.D. Monnery, M. Thanou, S. Shaunak and J.H.G. Steinke, Int. J. Pharm 2017, 521, 249-258. DOI: 10.1016/j.ijpharm.2017.02.048

[14] The effect of ionizing radiation on biocompatible polymers: From sterilization to radiolysis and hydrogel formation

O. Sedlacek, J. Kucka, B.D. Monnery, M. Slouf, M. Vetrik, R. Hoogenboom, and M. Hruby, Polym. Degrad. Stab. 2017, 137, 1-10. DOI: 10.1016/j.polymdegradstab.2017.01.005

[13] The label matters: μPET imaging of the biodistribution of low molar mass 89Zr and 18F-Labeled poly(2-ethyl-2-oxazoline)

M. Glassner, L. Palmieri, B.D. Monnery, T. Verbrugghen, S. Deleye, S. Stroobants, S. Staelens, L. wyffels, and R Hoogenboom, Biomacromolecules, 2017, 18, 96-102. DOI: 10.1021/acs.biomac.6b01392

[12] The chemistry of poly(2-oxazoline)s

B.Verbraeken, B.D. Monnery, K. Lava, and R. Hoogenboom, Eur. Polym J. 2017, 88, 451-469. DOI: 10.1016/j.eurpolymj.2016.11.016

[11] μPET imaging of the pharmacokinetic behavior of medium and high molar mass 89Zr-labeled poly (2-ethyl-2-oxazoline) in comparison to poly (ethylene glycol)

L. wyffels, T. Verbrugghen, B.D Monnery, M. Glassner, S. Stroobants, R. Hoogenboom, S. Staelens, J. Control. Release 2016, 235, 63-71. DOI: 10.1016/j.jconrel.2016.05.048

[10] Sulfolane as common rate accelerating solvent for the cationic ring-opening polymerization of 2-oxazolines

M. Vergaelen, B. Verbraeken, B.D. Monnery, and R. Hoogenboom, ACS Macro Lett. 2015, 4, 825–828. DOI: 10.1021/acsmacrolett.5b00392

[9] Synthesis of poly(2-oxazoline)s with side chain methyl ester functionalities: Detailed understanding of living copolymerization behavior of methyl ester containing monomers with 2-alkyl-2-oxazolines

P.J.M. Bouten, D. Hertsen, M. Vergaelen, B.D. Monnery, S.Catak, J.C.M. van Hest, V.V. Speybroeck, and R Hoogenboom, J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 2649-61. DOI: 10.1002/pola.27733

[8] Improved synthesis of linear poly(ethylenimine) via low-temperature polymerization of 2-isopropyl-2-oxazoline in chlorobenzene

B.D. Monnery, S. Shaunak, M. Thanou, and J.H.G. Steinke, Macromolecules 2015, 48 , 3197–3206. DOI: 10.1021/acs.macromol.5b00437

[7] Systematic investigation of alkyl sulfonate initiators for the cationic ring-opening polymerization of 2-oxazolines revealing optimal combinations of monomers and initiators

M. Glassner, D.R. D’hooge, J.Y. Park, P.H.M.V. Steenberge, B.D. Monnery, M-F Reyniers, and R. Hoogenboom, Eur. Polym. J. 2015, 65, 298-305. DOI: 10.1016/j.eurpolymj.2015.01.019

[6] Accelerated living cationic ring-opening polymerization of a methyl ester functionalized 2-oxazoline monomer

P.J.M. Bouten, D. Hertsen, M. Vergaelen, B.D. Monnery, M.A. Boerman, H. Goossens, S. Catak, J.C.M. van Hest, V.V. Speybroeck, and R Hoogenboom, Polym. Chem. 2015, 6, 514-518. DOI: 10.1039/C4PY01373E

[5] Synthesis and Modification of Poly(alkylenimine)s for Biomedical Applications

B.D. Monnery and R. Hoogenboom, Cationic Polymers in Regenerative Medicine, R.S.C. London 2015. DOI: 10.1039/9781782620105-00030

[4] Fast and accurate partial hydrolysis of poly (2-ethyl-2-oxazoline) into tailored linear polyethylenimine copolymers

R.V. de la Rosa, E. Bauwens, B.D. Monnery, B.G. De Geest, and R. Hoogenboom, Polym. Chem. 2015, 5, 4957-4964. DOI: 10.1039/C4PY00355A

[3] Cationic ring-opening polymerization of 2-propyl-2-oxazolines: understanding structural effects on polymerization behavior based on molecular modeling

H. Goossens, S. Catak, M. Glassner, V.R. de la Rosa, B.D. Monnery, F. De Proft, V.V. Speybroeck, and R. Hoogenboom, ACS Macro Lett. 2013, 2, 651-654. DOI: 10.1021/mz400293y

[2] Poly (2-oxazoline)s – are they more advantageous for biomedical applications than other polymers?

O. Sedlacek, B.D. Monnery, S.K. Filippov, R. Hoogenboom, and M. Hruby, Macromol. Rapid Commun. 2012, 33, 1648-1662. DOI: 10.1002/marc.201200453

[1] Bioresponsive small molecule polyamines as noncytotoxic alternative to polyethylenimine

C.R. Drake, A. Aissaoui, O. Argyros, J.M. Serginson, B.D. Monnery, M. Thanou, J.H.G. Steinke, and A.D. Miller, Mol. Pharmaceutics 2010, 7, 2040–2055. DOI: 10.1021/mp9002249

Conference Contributions

Oral Presentations

[8] Narrow distribution poly(2-oxazoline) homo- and block co-polymers without parasitic homopolymers

Belgian Polymer Group Annual Meeting 2017, Houffalize, Belgium

[7] The hydrolytic mechanism of polycationic toxicity: implications for polymeric transfection

ACS Meeting August 2016, Philadelphia, United States of America

[6] In vivo behavior of 89Zr-labeled poly(2-ethyl-2-oxazoline) and poly(ethylene glycol)

ACS Meeting August 2016, Philadelphia, United States of America

[5] Uniform block poly(2-oxazoline)s

ACS Meeting August 2016, Philadelphia, United States of America

[4] Uniform high molar mass poly(2-oxazoline)s

Living Polymerization 2016, Budapest, Hungary

[3] Uniform high molar mass homo-, block and statistical poly(2-oxazoline)s

Ionic Polymerization 2015, Bordeaux, France

[2] High molecular weight uniform poly (2-ethyl-2-oxazoline)

ACS Meeting September 2014, San Francisco, United States of America

[1] Synthesis of monodisperse linear poly(ethylenimine) with minimised structural defects as model compounds for elucidating cell membrane properties

European Polymer Congress 2011, Granada, Spain

Poster Presentations

[7] Elucidation of the poly(2-oxazoline) chain-transfer mechanism by chain length distribution analysis and probabilistic modelling

CHAINS 2018, Eindhoven, The Netherlands

[6] Thermoresponsive ABA triblock copoly(2-oxazoline)s as potential injectable hydrogels

APME 2017, Ghent, Belgium

[5] Thermoresponsive ABA Triblock Poly(2-oxazoline)s as Potential Injectable Hydrogels

CHAINS 2016, Eindhoven, The Netherlands

[4] Uniform high molar mass poly(2- oxazoline)s as PEG alternatives

CHAINS 2015, Eindhoven, The Netherlands

[3] Functional poly(2-oxazoline)s via transamidation of side-chain esters

European Polymer Congress 2013, Pisa, Italy

[2] Synthesis of monodisperse poly(oxazoline)s to determine the structure-activity relation of linear poly(ethylenimine)

European Society for Gene and Cell Therapy 2011, Brighton, United Kingdom

[1] The synthesis of linear poly(alkylenimine)s as tools to determine the effects on cellular membranes

Frontiers of Polymer Science / Young Researchers Meeting 2009, Nottingham, United Kingdom

Education

2007-2012

Postgraduate student

PhD Chemistry



Imperial College London (UK)

Experience

2019-

Postdoctoral Researcher

Polymer Reaction Design Group

Hasselt University (BE)

2012-2017

Postdoctoral Researcher

Supramolecular Chemistry Group

Ghent University (BE)

2007-2012

PhD Chemistry

Imperial College London (UK)